“Recognizing and preventing men’s health problems is not just a man’s issue. Because of its impact on wives, mothers, daughters, and sisters, men’s health is truly a family issue,” declared Congressman Bill Richardson, who made the remark as part of the 1994 resolution establishing the first National Men’s Health Week. It was created to elevate understanding of preventable men’s-specific health conditions, and to encourage early detection. This year, Men’s Health Awareness Week is June 14 to 21.
Testosterone is the most well-known hormone representing male virility as reduced levels are directly associated with depressed libido and impaired sexual function. According to a 2025 review, beyond sexual dimorphism, testosterone plays roles in metabolic processes, bone density and mood regulation in men. A new study funded by the National Institutes of Health has discovered a potential new ability of testosterone – suppressing brain tumor growth in men. Researchers found that mice with significant androgen loss showed accelerated intracranial tumor growth through activation of the hypothalamic-pituitary-adrenal axis. This area, of course, needs further exploration, but it is intriguing.
Decline of the Big T
So many commercials for testosterone-boosting products feature older men, but unfortunately, younger men are living with less-than-optimal testosterone production. And this means a new target audience for supplementation.
Generationally, men are losing testosterone, as shown by several population studies through the years — average testosterone levels have declined by approximately 1% every year since the late 1980s. According to a 2007 study, a 60-year-old man in 1987 had a median total testosterone level of 17.5 nmol/L; in 2002, a 60-year-old man averaged closer to 15 nmol/L.
Gen Z and Millennials in their 20s and 30s tend to have noticeably lower testosterone compared with previous generations of men at the same ages. Men’s health specialist Ryan Meade, MD, commented, “A young man today may have testosterone levels that would have been considered low or borderline for his grandfather at the same stage of life.”
Even with average lower testosterone than their fathers and grandfathers, many Millennial men are feeling the effects of declining, sluggish testosterone production. Often beginning in the late 30s, fat more easily accumulates around the mid-section, and energy levels are more quickly depleted; it’s also more difficult to achieve and maintain gains in muscle mass and strength. In the late 40s, more men notice that the sexual get-up -and-go is still sitting down. Nearly 70% of men diagnosed with low testosterone report problems with erectile dysfunction and 63% report lowered sex drive.
Low T is also known as testosterone deficiency, which is a characteristic of male hypogonadism (HG), described as a “clinical syndrome related to the inadequate production of testosterone (androgen deficiency) and reduced spermatogenesis.” The authors note that the prevalence of hypogonadism rises with age, ranging from 12% among men in their 50s to 49% among those 80 years and older. A diagnosis of low testosterone is usually measured by levels of 300ng/dl or lower.
According to Western Michigan Urological Associates, testosterone levels decrease by about 1% per year starting in a man’s late 30s or early 40s. Breaking it down, stats show:
As men age, they can also develop a condition known as Androgen Deficiency of Aging Males (ADAM), which largely manifests as sexual symptoms; erectile dysfunction is one of the most common symptoms of ADAM.
The LJ100® Solution
The most-studied Tongkat Ali (Eurycoma longifolia), LJ100® is the only Tongkat Ali that is protected by a worldwide patent for support of sexual function, increased testosterone, and improved male fertility. The patent is entitled, “Bioactive Eurypeptides isolated in Tongkat Ali that is proven to be the active compounds effective for treatment of sexual dysfunction, male infertility, and increased testosterone.”
LJ100® is distinguished by the research demonstrating its long-term ability to help men enjoy the benefits of healthy testosterone production. There are quite a few studies on LJ100® and men’s health; here are just a few. Researchers looked at effects of concurrent training and supplementation with 200 mg E. longifolia (as LJ100®) on erectile function and testosterone levels in men with ADAM. The 6-month study randomized 45 middle-aged men into 4 groups (G1: control + placebo; G2: control + Eurycoma longifolia; G3: concurrent training + placebo; G4: concurrent training + Eurycoma longifolia). The researchers focused on improvement in the five domains of sexual health — erectile function, sexual satisfaction, sexual desire, orgasmic function and general satisfaction.
The most significant progress in the sexual block of the Aging Male Symptoms Scale occurred for men in the training and LJ100® group (G4). Men in the G3 (concurrent training + placebo), showed improvement in the five domains up to the 4th month, which subsided by month 6. Men in the training-only group showed gradual improvement of the five domains, reaching their highest value at month 6. The researchers concluded that supplementing with 200 mg LJ100® with concurrent training for 6 months significantly improved the erectile function of men with ADAM.
In another 6-month study of the same cohort of men with Androgen Deficiency of Aging Males (ADAM), the researchers analyzed the effects of concurrent training associated with LJ100® supplementation in the muscle strength, cardiorespiratory fitness, ADAM symptom scores, testosterone levels, body fat, waist circumference, and serum lipid profiles. The results showed that the concurrent training, alone or combined with LJ100® supplementation, significantly improved the isometric and isokinetic knee extension and flexion muscles strength, testosterone levels, cardiorespiratory fitness, and ADAM symptomatology.
In a 12-week study, 105 men aged 50-70 with testosterone level less than 300ng/Dl (low T), supplemented with either 100 mg, 200 mg of LJ100® or placebo. In the 200 mg group, total testosterone increased 12.2% and free testosterone increased 16.9%. Cortisol levels significantly decreased in the LJ100® 200 mg group, while muscle strength significantly increased in both LJ100® groups at week 12 in the within-group comparison. Additionally, researchers observed significant decreases in Aging Male Score and fatigue score for both LJ100® groups. This study demonstrates that LJ100® also promotes favorable anabolic balance (increased testosterone, reduced cortisol).
A another 12-week study compared the effects of 300 mg LJ100® or placebo on sexual health in 109 healthy men aged 30 to 55. The LJ100® group showed higher scores in the overall Erectile Function domain in International Index of Erectile Function, sexual libido (14% by week 12). Additionally, sperm fluid analysis showed that sperm motility increased 44% (from 33.8% to 48.8%), and semen volume also increased 18.2% (from 2.54ml to 3.00ml) in the LJ100® group. Another benefit of LJ100®: overweight subjects (higher than 25kg BMI) experienced fat mass loss in the abdominal area compared to placebo.
Why LJ100®?
LJ100® Tongkat Ali offers a proven foundation for vitality-focused SKUs in the men’s health category — whether you’re formulating for men navigating andropause, maintaining testosterone levels, or simply promoting long-term wellness. Its clinically demonstrated abilities to elevate free testosterone, reduce cortisol, and enhance wellness biomarkers make LJ100® an ideal fit for formulas designed for men concerned about flagging testosterone levels. With broad compatibility across capsules, powders, and functional blends, LJ100® Tongkat Ali empowers brands to build differentiated products for the growing men’s health and longevity markets.
