As reported in Natural Products Insider:
A patented extract of Andrographis Paniculata (as ParActin™ from HP Ingredients) administered at 100f mg/d for 14 weeks decreased the intensity of joint pain in patients with rheumatoid arthritis (RA) compared to placebo in a 2009 study.¹ Those who took the botanical also had fewer tender joints and number of swollen joints. Patients treated with ParActin also showed improvement in CRP from above normal to a normal level, and demonstrated an ability to normalize immunoglobin (Ig) A and IgM. The reduction in IgA and IgM is beneficial as there is positive correlation between the grade of cartilage damage.
In another study from 2013, 300 mg/d of ParActin for four years significantly improved total grade of tender joints and quality of life in patients with various rheumatoid conditions.² In addition, researchers found a significant reduction in Rheumatoid Factor and CRP.
¹Burgos R et al. “Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.” Clin Rheumatol. 2009 Aug;28(8):931-46. DOI: 10.1007/s10067-009-1180-5.
²Hidalgo M et al. “Andrographolide a New Potential Drug for the Long Term Treatment of Rheumatoid Arthritis Disease.” Innovative Rheumatology. 2013 DOI: 10.5772/55642.
By Kate Lloyd, Celeste Sepessy and Sandy Almendarez
Source: Natural Products Insider
