In this edutaining episode, Gene Bruno and Dr. Annie George describe the amazing health benefits of IQ200®, a standardized water extract derived from the leaves of Kesum (Polygonum minus), known for its potential health benefits. It has been the subject of four published human clinical studies demonstrating its efficacy, along with toxicology studies confirming its safety.
The Kesum plant, native to Malaysia, is known as “Smart Weed”. It is rich in glucuronides, flavonoids, and antioxidants. Clinical studies have shown it to improve memory, reduce inflammation, and modulate the immune system.
5 Key Benefits of IQ200®
- Cognitive Function: IQ200® increases brain-derived neurotrophic factor (BDNF) +2.03% vs placebo -19.19% (p,0.05), improves memory by +9.8% vs placebo -6.8% (p,0.012) as measured by Visual Reproduction II. These support neuron growth and health, and inhibits the catabolic enzyme acetylcholinesterase, thereby enhancing acetylcholine levels to improve memory. It also stimulates the prefrontal cortex and reduces oxidative stress biomarkers.
- Potential for Mental Health: Based on its effects on mood and stress in animal models of vascular dementia and depression, IQ200® shows promise for supporting mental health by reducing anxiety and stress.
- Mood and Stress: Clinical studies revealed significant reductions in stress-related mood scores: anger by -52.95%, tension -30.91%, confusion -44.5%, and total negative subscales -33.43%, suggesting IQ200® has calming effects. Animal studies indicate it may improve serotonin and GABA levels, as well as reduce corticosterone (a stress hormone).
- Inflammation: IQ200® has shown anti-inflammatory effects in animal studies, including reducing paw edema (swelling) and improving osteoarthritis symptoms by reducing pro-inflammatory markers like TNF-alpha and IL-6.
- Skin Health: Topical application of IQ200® in a cream has been shown to reduce appearance of wrinkles (particularly crow’s feet) by inhibiting collagenase, an enzyme that breaks down collagen.
Structure Function Claims for IQ200®
- Promotes focus and memory retention*
- Encourages faster neural processing speeds*
- Enhances working memory, cognitive flexibility, and executive function*
- Helps inhibit inflammation markers to promote brain function*
- Promotes healthy brain and cognitive function*
- Promotes healthy neurochemical balance*
- Encourages a healthy mood, and supports emotional well-being*
Conclusion:
Studies thus far have suggested that IQ200® offers a wide range of benefits, including cognitive enhancement, inflammation reduction, skin rejuvenation, and stress relief, making it highly versatile supplement to address common health concerns.
