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Welcome to HPI Hemp-Derived Cannabidiol Products
Safe, Compliant, & Sustainably Harvested
- Manufactured in cGMP, USDA-Certified Organic, and FDA-registered facilities
- C02 Extraction or Ethanol Extraction
- Standardized products
- Custom Cannabinoids Products: Each batch is made to order according to clients’ special requirements
- 4 times full-panel testing from farm crop, pre-production, pos- production, and at HPI warehouse.
- 3rd-Party Testing Labs: Botanacor or Eurofins
What is CBD?
How Does CBD Work in Our Bodies?
- CBD interacts with the naturally occurring cannabinoid receptors
- The human body naturally produces cannabinoid receptors, known as the Endogenous Cannabinoid System (ECS), which regulates sleep patterns, pain sensation, and immune system functions
- ECS is split into two main receptors: CB1 and CB2
- CB1 Receptors: appetite, sleep, general sense of well-being, memory, and pain
- CB2 Receptors: immune and nervous systems
- CBD activates certain receptors and inhibits others
Health benefits of CBD
Before HPI…
Traditional CBD oil contains large liposomes that are difficult for the body to digest: only 6%-10% makes it through the digestive system and into the bloodstream — 90% is wasted.
Some nano products measure as high as 1000nm with a broad distribution of particle sizes. These large liposomes cannot be transported transcellularly and are slowed down in the GI environment.
Our Solution:
- Fast-acting, high absorption, water-soluble delivery system
- Produced at pharmaceutical-grade manufacturing facility
- Highly bioavailable nanoparticles, 20-70 nanometers (nm)
- More surface area, more stable, uniform, and tightly distributed unilamellar liposome spheres for enhanced bioavailability
- Absorbed upon immediate contact with skin as topical, or sublingual through mucous membranes of the mouth, upper gastrointestinal tract and stomach, avoiding absorption constraints normally posed by the small intestine.
- Absorption rate: almost at 100%
Fast Absorption Nano-emulsified Cannabidiol
- Fast absorption time = 25 mins vs 110 mins
- 7X efficacy compared to non-nano-emulsified cannabidiol
- Less product is required for effective dose management:
- 10mg = 70mg of CBD tincture
- Beverages, tinctures, blending, baked goods, pet products, topicals
- 40-50 nanometers
We offer:
- 10% or 20% Water-Soluble Broad-Spectrum CBD Liquid Concentrate
- 10% Water-Soluble Broad-Spectrum CBN Liquid Concentrate
Organic Hemp Tea Leaves
- Offers the benefits of the whole plant
- Great for blending
- Excellent as a loose-leaf tea
- THC <0.3%
- Shelf Life: 24 months, unopened
Water Soluble Product Applications
- RTD Beverage, Juices, Smoothies
- Additives for drinks, tea and coffee houses
- Single-serving packet beverage powder
- Food Manufacturing
- Tinctures
- Spray on tea leaves
- Topicals: Lotions, cosmetics, skin and hair care
- Chocolates, confectionery, candy
- Frozen desserts
- Supplements: Capsules, tablets
- Companion pet products: Pet treats
- Livestock products: Pellets
The Big 6 Cannabinoids
Research shows:
- CBD affects stress, tension, healthy inflammatory response, cognitive function, and mor
- CBN affects sleep, healthy inflammatory response
- CBG affects energy, focus, bone morphology, bowel function and vision health
- CBC affects skin, mood, brain structure and function, and healthy inflammatory response
- THCV affects central nervous system and brain structure and function
- THC affects chronic discomfort, healthy muscle contraction, and healthy inflammatory response
These statements are not claims. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure or prevent disease.
113 Different Cannabinoids
CBDA
Supports healthy inflammatory response. Encourages healthy cellular metabolism.
CBG
Aids sleep, Encourages healthy cellular metabolism, Supports healthy
bone turnover, Slows bacterial growth
CBGA
Supports healthy inflammatory response, Reduces discomfort, Slows bacterial
growth
THCV
Supports healthy bone turnover
Delta 8-THC
Reduces discomfort
Delta 9-THC
Supports healthy upper GI function, Reduces discomfort, Stimulates appetite, Supports healthy muscle contraction
Delta 9-THCA
Aids sleep, Encourages healthy cellular metabolism, Supports healthy
muscle contraction
CBCA
Supports healthy inflammatory response, Treats Fungal Infection
CBC
Encourages healthy cellular metabolism, Supports healthy bone turnover, Supports healthy inflammatory response, Reduces discomfort
The Human Endocannabinoid System
CBD, CBN, and THC fit like a lock and key into existing human receptors.
These receptors are part of the
Endocannabinoid System which impact physiological processes affecting pain modulation, memory, and appetite. This system also impacts inflammatory and specific immune responses.
The Endocannabinoid System comprises two types of receptors, CB1 and CB2, which serve distinct functions in human health and
well-being.
Endocannabinoid System which impact physiological processes affecting pain modulation, memory, and appetite. This system also impacts inflammatory and specific immune responses.
well-being.
Receptors are found on cell surfaces
- CB1 receptors are primarily found in the brain and central nervous system, and to a lesser extent in other tissues.
- CBD does not directly “fit” CB1 or CB2 receptors but has powerful indirect effects still being studied
- CB2 receptors are mostly in the peripheral organs especially cells associated with the immune system.
Water-Soluble Hemp-Derived Cannabinoid Powders
- <500-3000 nanometers (not described as nano-emulsions)
- Can be conveniently blended into liquids
- Longer shelf life
- Can be used for capsules, topicals, baked goods, pet foods, cosmetics, powdered drinks, and beverages
- 10% and 20% CBD Isolate Water-Soluble Powder (0% THC)
- 10% and 20% Broad-Spectrum CBD Water-Soluble Powder (ND THC)
- 10% and 20% Full-Spectrum CBD Water-Soluble Powder (<0.3% THC)
Other & Custom Cannabinoid Products
- 99% CBD Isolate Powder
- Organic Hemp Tea Leaf
- Minor Cannabinoids: CBG, CBN, CBC
Vertical Compliant Supply Chains
Every farm is:
- Licensed & insured
- In compliance with 2014 & 2018 USDA Farm Bill requirement
- GACP – Good Agricultural Collection Practices
- Pesticides free
- Capable of producing up to 1M pounds each harvest with consistent genetics
If compliance guidance is required, our consultants are ready to help.
- Non-GMO
- Pesticides Free
- Herbicides Free
- No Chemical Fertilizers
- Grown in Colorado
- Certified Organic Available
- In Compliance with US and EU Standards
Dosage:
Dosage depends on body weight, condition you are treating, and individual body chemistry.
Human studies use dosages 20 – 1500 milligrams (mg) per day.
Everyone’s endocannabinoid system responds uniquely to cannabinoids. One person may only need 1-5 mg when another needs 10-20 mg.
Recommendation: Start low and slow, adding until the desired effect is achieved. https://www.healthline.com/health/cbd-dosage
References:
- An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis Cannabinoid Research. 2017 Jun 1;2(1):139-154. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/
- Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent Mateus Machado Bergamaschi 1, Regina Helena Costa Queiroz, Antonio Waldo Zuardi, José Alexandre S Crippa
- Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent DOI: 10.2174/157488611798280924
- Cannabis therapy. Dtsch Arztebl Int. 2013 Mar;110(9):144. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601285/
- Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. J Cannabis Research . 2021 Jul 2;3(1):22. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252988/
- Duration of Untreated Disorder and Cannabis Use: An Observational Study on a Cohort of Young Italian Patients Experiencing Psychotic Experiences and Dissociative Symptoms. Int J Environ Res Public Health. 2021 Nov 30;18(23):12632.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657003/
- Cannabis use as a moderator of cognitive behavioral therapy for insomnia. J Clin Sleep Med. 2021 Dec 7. doi: 10.5664/jcsm.9796
- Cancer Treatment: Preclinical & Clinical. J Natl Cancer Inst Monogr. 2021 Nov 28;2021(58):107-113. doi: 10.1093/jncimonographs/lgab010.
- Effects of cannabidiol in the treatment of patients with Parkinson’s disease: an exploratory double-blind trial. J Psychopharmacol. 2014 Nov;28(11):1088-98. https://pubmed.ncbi.nlm.nih.gov/25237116/
Human studies use dosages 20 – 1500 milligrams (mg) per day.
Everyone’s endocannabinoid system responds uniquely to cannabinoids. One person may only need 1-5 mg when another needs 10-20 mg.
Recommendation: Start low and slow, adding until the desired effect is achieved. https://www.healthline.com/health/cbd-dosage
HPI's Custom Formulations
HP Ingredients offers custom formulations and private labeling services to manufacturers. HPI’s innovation in formulations is accomplished by combining our trademarked ingredients with other clinically tested, well-researched nutraceuticals.